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Carnitine congener mildronate protects against stress- and haloperidol-induced impairment in memory and brain protein expression in rats
(Elsevier, 2014)
The present study investigates the efficacy of mildronate, a carnitine congener, to protect stress and haloperidol-induced impairment of memory in rats and the expression of brain protein biomarkers involved in synaptic ...
γ1- and γ2-melanocyte stimulating hormones induce central anxiogenic effects and potentiate ethanol withdrawal responses in the elevated plus-maze test in mice
(Elsevier, 2009)
Little is known about the endogenous functions of γ1- and γ2-melanocyte stimulating hormones (γ1- and
γ2-MSH). Although γ-MSHs bind to melanocortin receptor subtypes 3 and 4, we have previously shown that
these peptides ...
Intranasal Administration of Extracellular Vesicles Derived from Human Teeth Stem Cells Improves Motor Symptoms and Normalizes Tyrosine Hydroxylase Expression in the Substantia Nigra and Striatum of the 6-Hydroxydopamine-Treated Rats
(AlphaMed Press Wiley, 2019-04-22)
Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting millions of people worldwide. At present, there is no effective cure for PD; treatments are symptomatic and do not halt progression ...
Lunasin-induced behavioural effects in mice: Focus on the dopaminergic system
(Elsevier, 2013)
The present study for the first time is devoted to identify central effects of synthetic lunasin, a
43 amino acid peptide. A markedly expressed neuroleptic/cataleptic effect was observed at low
(0.1–10 nmol/mouse) centrally ...