No klīniskā materiāla izdalīto E.coli un Klebsiella Spp. baktēriju jutības noteikšana pret antibakteriālajiem līdzekļiem un to kombinācijām ar ēteriskajām eļļām
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Latvijas Universitāte
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lav
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Aktualitāte: Antibakteriālā rezistence ir pasaules mēroga problēma, līdz ar to ir svarīgi meklēt jaunas iespējas infekciju ārstēšanai. Potenciāla alternatīva, iespējams, ir ēteriskās eļļas. Mērķis: Noteikt laboratorijā izdalīto E. coli un Klebsiella sugu jutību pret antibiotikām un ēteriskajām eļļām, izmantojot mikrobioloģisko metodi un statistisko apstrādi. Rezultāti: 242 E. coli un 214 Klebsiella paraugu vidū ESBL producē 7,85% E.coli un 11,21% Klebsiella spp. paraugi. Vislabākā jutība konstatēta pret meropenēmu/imipenēmu, kas atbilstoši ir 99,59% un 99,53%, un vismazākā pret ciprofloksacīnu – Klebsiella spp. – 86,45%, E. coli - 91,74%. No trim pētāmajām eļļām, vislabākā antibakteriāla iedarbība ir Origanum vulgare, bet vismazākā efektivitāte - Rosmarinus officinalis.
SUMMARY The topicality of the research: Antibacterial resistance is a global problem, so it is important to look for new ways to treat infections. The most promising alternatives are essentials oils. Aim of the work: To determine the susceptibility of E. coli and Klebsiella species isolated in the laboratory to antibiotics and essential oils using a microbiological method and statistical treatment. Results: Among 242 E. coli and 214 Klebsiella samples, ESBL produces 7.85% E. coli and 11.21% Klebsiella spp. examples. The best susceptibility was found for meropenem / imipenem, which is 99.59% and 99.53%, respectively, and the lowest for ciprofloxacin, Klebsiella spp. - 86.45%, E. coli - 91.74%. Of the three oils studied, Origanum vulgare showed the most prominent antibacterial activity, while Rosmarinus officinalis had the lowest effifacy.
SUMMARY The topicality of the research: Antibacterial resistance is a global problem, so it is important to look for new ways to treat infections. The most promising alternatives are essentials oils. Aim of the work: To determine the susceptibility of E. coli and Klebsiella species isolated in the laboratory to antibiotics and essential oils using a microbiological method and statistical treatment. Results: Among 242 E. coli and 214 Klebsiella samples, ESBL produces 7.85% E. coli and 11.21% Klebsiella spp. examples. The best susceptibility was found for meropenem / imipenem, which is 99.59% and 99.53%, respectively, and the lowest for ciprofloxacin, Klebsiella spp. - 86.45%, E. coli - 91.74%. Of the three oils studied, Origanum vulgare showed the most prominent antibacterial activity, while Rosmarinus officinalis had the lowest effifacy.