Farmakovigilance un psihotropo zāļu patēriņš Latvijā
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Latvijas Universitāte
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Abstract
Promocijas darbs veltīts farmakovigilances sistēmas ieviešanas un psihotropo zāļu
patēriņa pētījumiem. Paralēli negaidīto blakus efektu (adverse drug reactions (ADR))
ziņojumu statistikas un psihotropo zāļu patēriņa statistikas pētījumiem veikta farmaceitu
un farmaceitu asistentu aptauja. Latvijā farmaceitiem ir ļoti maza pieredze
farmakovigilances pētījumos un farmaceiti baidās dot viltus informāciju. ADR atklāšanu
traucē datu bāzu par medikamentu pārdošanu pacientiem trūkums. Psihotropo zāļu
patēriņa pētījumus mēs veicām Latgalē un Rīgā. Antidepresantu patēriņu pētījām Rīgā un
reģionos. Mūsu pētījums parādīja, ka antidepresantu patēriņš Latvijā ir daudz mazāks
nekā citās Eiropas valstīs. Zāļu patēriņa aprēķinus definētajās diennakts devās uz 1000
iedzīvotājiem dienā papildinājām ar farmaceitu aptauju datiem, kuri apliecināja zāļu cenu
nozīmi pacienta lēmuma pieņemšanā par zāļu pirkšanu, kā arī garīgo pacientu bažas par
viņu atstumšanu sabiedrībā.
Atslēgvārdi: Farmakovigilance, farmaceiti, farmaceitu asistenti, psihotropās zāles,
aptauja.
The doctoral thesis is devoted to studies on pharmacovigilance system in Latvia and use of psychotropic drugs. In parallel with studies on statistics of adverse drug reactions (ADR) reporting, we surveyed pharmacists and pharmacist’s assistants to reveal reasons that hamper ADR reporting. We found that ADR reporting activity is low and pharmacists are afraid to give false reports, as well as they do not have access to patient’s medication data basis. Studies on use of psychotropic drugs we carried out in Latgale and in Riga, but use of antidepressants in regions and Riga. The use of antidepressants in Latvia is much lower than in other EU countries. Additionally to the calculated use of psychotropic drugs in defined daily dose per 1000 inhabitants per day, we surveyed pharmacists and pharmacist’ assistants. The obtained data confirm the impact of drug price on patient’s decision to buy or not medicine and mental patients worries about their rejection in society. Key words: Pharmacovigilance, pharmacists, pharmacist assistant, psychotropic drugs, survey.
The doctoral thesis is devoted to studies on pharmacovigilance system in Latvia and use of psychotropic drugs. In parallel with studies on statistics of adverse drug reactions (ADR) reporting, we surveyed pharmacists and pharmacist’s assistants to reveal reasons that hamper ADR reporting. We found that ADR reporting activity is low and pharmacists are afraid to give false reports, as well as they do not have access to patient’s medication data basis. Studies on use of psychotropic drugs we carried out in Latgale and in Riga, but use of antidepressants in regions and Riga. The use of antidepressants in Latvia is much lower than in other EU countries. Additionally to the calculated use of psychotropic drugs in defined daily dose per 1000 inhabitants per day, we surveyed pharmacists and pharmacist’ assistants. The obtained data confirm the impact of drug price on patient’s decision to buy or not medicine and mental patients worries about their rejection in society. Key words: Pharmacovigilance, pharmacists, pharmacist assistant, psychotropic drugs, survey.