Potenciālu IRE1a inhibitoru sintēze
| dc.contributor.advisor | Kļimenkovs, Igors | |
| dc.contributor.author | Šadauskis, Jānis | |
| dc.contributor.other | Latvijas Universitāte. Ķīmijas fakultāte | |
| dc.date.accessioned | 2023-09-06T01:03:17Z | |
| dc.date.accessioned | 2025-07-22T12:11:12Z | |
| dc.date.available | 2023-09-06T01:03:17Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | Bakalaura darba ietvaros tika sintezēti aizvietoti 1H-1,2,4-triazol-5-amīni, kā arī oksazolamīni un pirazolamīni, kas varētu būt potenciāli IRE1α inhibitori. Tika pētīta 1H-1,2,4-triazol-5-amīnu acilēšana un endocikliski acilēto savienojumu izomerizācija par eksocikliski acilētiem savienojumiem. | |
| dc.description.abstract | Bachelor’s thesis is dedicated to the synthesis of substituted 1H-1,2,4-triazol-5-amines as well as substituted oxazolamines and pyrazolamines, that could be potential inhibitors of IRE1α. Acylation of 1H-1,2,4-triazol-5-amines and endocyclically acylated compound isomerization into exocyclically acylated compounds was investigated. | |
| dc.identifier.other | 96515 | |
| dc.identifier.uri | https://dspace.lu.lv/handle/7/64193 | |
| dc.language.iso | lav | |
| dc.publisher | Latvijas Universitāte | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Ķīmija | |
| dc.subject | IRE1a | |
| dc.subject | IRE1a INHIBITORI | |
| dc.subject | 1,2,4-TRIAZOL-5-AMĪNU ACILĒŠANA | |
| dc.subject | OKSAZOLAMĪNI | |
| dc.subject | PIRAZOLAMĪNI | |
| dc.title | Potenciālu IRE1a inhibitoru sintēze | |
| dc.title.alternative | Synthesis of potencial IRE1a inhibitors | |
| dc.type | info:eu-repo/semantics/bachelorThesis |