Browsing Publicēti raksti (MF) / Published Articles by Author "Pupure, Jolanta"
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Intranasal Administration of Extracellular Vesicles Derived from Human Teeth Stem Cells Improves Motor Symptoms and Normalizes Tyrosine Hydroxylase Expression in the Substantia Nigra and Striatum of the 6-Hydroxydopamine-Treated Rats
Narbute, Karīna; Piļipenko, Vladimirs; Pupure, Jolanta; Dzirkale, Zane; Jonavičė, Ugnė; Tunaitis, Virginijus; Kriaučiūnaitė, Karolina; Jarmalavičiūtė, Akvilė; Jansone, Baiba; Kluša, Vija; Pivoriūnas, Augustas (AlphaMed Press Wiley, 2019-04-22)Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting millions of people worldwide. At present, there is no effective cure for PD; treatments are symptomatic and do not halt progression ... -
Very low doses of muscimol and baclofen ameliorate cognitive deficits and regulate protein expression in the brain of a rat model of streptozocin-induced Alzheimer's disease
Pilipenko, Vladimirs; Narbute, Karina; Beitnere, Ulrika; Rumaks, Juris; Pupure, Jolanta; Jansone, Baiba; Klusa, Vija (Elsevier, 2018-01-05)Recent studies devoted to neuroprotection have focused on the role of the gamma-aminobutyric acid (GABA) system in regulating neuroinflammatory processes which play a key role in the neurodegenerative processes observed ... -
γ1- and γ2-melanocyte stimulating hormones induce central anxiogenic effects and potentiate ethanol withdrawal responses in the elevated plus-maze test in mice
Jansone, Baiba; Rumaks, Juris; Dzirkale, Zane; Pupure, Jolanta; Svirskis, Šimons; Muceniece, Ruta; Klusa, Vija (Elsevier, 2009)Little is known about the endogenous functions of γ1- and γ2-melanocyte stimulating hormones (γ1- and γ2-MSH). Although γ-MSHs bind to melanocortin receptor subtypes 3 and 4, we have previously shown that these peptides ...