Fotopletizmogrāfisko biosignālu formas analīze un asinsrites dinamikas modelēšana
Loading...
Date
Authors
Advisor
Journal Title
Journal ISSN
Volume Title
Publisher
Latvijas Universitāte
Language
lav
Abstract
Darbā pētītas iespējas diagnosticēt asinsvadu stāvokli, veicot fotopletizmogrāfisko biosignālu analīzi atbilstoši hemodinamikas modeļiem. Izveidota eksperimentāla in vitro sistēma vesela, hipertonijas un aterosklerozes stāvokļa simulācijai. Izstrādāta metodika un veikti klīniskie biosignālu mērījumi veseliem cilvēkiem un sirdsasinsvadu slimniekiem ortostatiskā un fiziskā testa laikā. Izstrādāts datu bāzes interfeiss biosignālu digitālai apstrādei. Demonstrēta iespēja aproksimēt biosignālu formu ar četru Gausa funkciju superpozīciju. Katrā sirdsdarbības ciklā noteikts pulsa cikla ilgums, pulsa viļņa izplatīšanās un atstarotā viļņa aizkaves laiki, augmentācijas indekss, refleksijas indekss un analizētas šo parametru korelācijas. Demonstrēta iespēja statistiski atdalīt veselo personu un perifēro artēriju oklūziju slimnieku grupas.
In this work the possibility of diagnosing cardiovascular conditions by analysing photopethysmographic signals corresponding to hemodynamic models was studied. An in vitro simulation of healthy, hypertensive, and arterosclerotic systems was developed. A signal measurement protocol was developed and applied to healthy subjects and cardiovascular patients during at orthostatic and a physical tests. A database interface was developed to process biosignals. It was shown that a signal shape can be fitted as a superposition of four Gaussians. In each heartbeat, pulse duration, transit times of the direct and reflected waves, augmentation and reflection indexes were calculated, correlations among these parameters were analysed. Possibility of the separation of healthy persons and patients of peripheral arterial occlusion have been demonstrated.
In this work the possibility of diagnosing cardiovascular conditions by analysing photopethysmographic signals corresponding to hemodynamic models was studied. An in vitro simulation of healthy, hypertensive, and arterosclerotic systems was developed. A signal measurement protocol was developed and applied to healthy subjects and cardiovascular patients during at orthostatic and a physical tests. A database interface was developed to process biosignals. It was shown that a signal shape can be fitted as a superposition of four Gaussians. In each heartbeat, pulse duration, transit times of the direct and reflected waves, augmentation and reflection indexes were calculated, correlations among these parameters were analysed. Possibility of the separation of healthy persons and patients of peripheral arterial occlusion have been demonstrated.